Anti-GPR126, C-Terminal antibody produced in rabbit, approx. 1 mg/mL, affinity isolated antibody, buffered aqueous solution

Biochem/physiol Actions

GPR126 (adhesion G protein-coupled receptor G6) controls the homeostasis of periodontal ligament tissue. GPR126 is responsible for axon myelination of peripheral neurons in human, mice and fish. This gene mediates endothelial cell proliferation and migration, and tube formation, thereby contributing to angiogenesis, which is necessary for overall growth, wound healing and tumor progression.

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General description

The GPR126 (adhesion G protein-coupled receptor G6) gene codes for a protein that contains an extracellular domain, a seven transmembrane domain at the N-terminal and an intracellular domain in its C-terminal.

G protein-coupled receptor 126 (GPR126) belongs to the adhesion-G protein-coupled receptor (GPCR) family. It is an endothelial cell-enriched gene. The gene is located on human chromosome 6q24.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human GPR126.Immunogen Range: 1091-1140

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.